Hirschsprung's disease in adults.
نویسندگان
چکیده
Hirschsprung's disease is the malformation of the hindgut characterised by the absence of intramural ganglion cells in the submucosal and myenteric plexuses and manifested by megacolon. Congenital character of this disease stipulates its belonging in general to the scope of activity of the pediatric clinics. Thanks to the progress of the pediatricians problems of diagnosis and treatment of Hirschsprung's disease have been successfully resolved.
منابع مشابه
[Hirschsprung's disease in adolescents and adults].
Megacolon must be considered as a diagnosis in any case of intractable constipation also in the adult. Besides the Hirschsprung's disease and the idiopathic megacolon, which have no apparent organic cause, many other pathologic conditions may produce a marked dilatation of the large bowel. The differential diagnosis depends, after a valuation of the clinical and radiologic features, also from e...
متن کاملDiagnostic Value of Calretinin and S100 Immunohistochemistry in Hirschsprung's Disease
Background Rectal biopsy and its histopathological study with hematoxylin and eosin (HE) is the gold standard for Hirschsprung's disease (HD) diagnosis. However, there are some limitations in the diagnosis of ganglion cells in HE approach. Recently, it was reported that the utility of Calretinin is a reliable ancillary immunohistochemistry (IHC) test for HD diagn...
متن کاملHirschsprung's disease in adults: report of a case and review of the literature.
Hirschsprung's disease in the adult is a rare and frequently misdiagnosed cause of long-standing refractory constipation. We report a case of Hirschsprung's disease in a 23-year-old man and review the literature. The patient had a history of chronic constipation that required daily enemas, since early infancy, but he had remained in good health until intestinal obstruction developed. As a subem...
متن کاملTreatment.
Hirschsprung's disease (congenital megacolon) is widely known as a disease of neonatal to childhood. Presentation in adulthood doesoccur but is rare. To date only 49 cases have been reported in the literature. We presented an additional case of adult Hirschsprung'sdisease (HD) to enrich the literature and to create an awareness of its existence in adults presenting with chronic constipa...
متن کاملHistochemical diagnosis of Hirschsprung's disease and a comparison of the histochemical and biochemical activity of acetyicholinesterase in rectal mucosal biopsies
Three hundred and seventy-two rectal mucosal biopsies, taken from 150 children and young adults with chronic constipation, were subjected to histochemical and biochemical analysis of acetylcholinesterase to exclude Hirschsprung's disease. The relative merits of the procedures were compared. The histochemical method was considered to be the most practical for laboratories handling small numbers ...
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ورودعنوان ژورنال:
- Acta chirurgica Iugoslavica
دوره 53 2 شماره
صفحات -
تاریخ انتشار 2006